By Judah Folkman (auth.), William D. Figg, Judah Folkman (eds.)
Dr. Judah Folkman, “father of angiogenesis”, (1933-2008) used to be the Director of the Vascular Biology software, Andrus Professor of Pediatric surgical procedure, and Professor of mobilephone Biology at Harvard University's Boston kid's health center. within the 1971 factor of the hot England magazine of drugs, he proposed the speculation that tumor development is angiogenesis established. This premise used to be the root of this box of analysis and has turn into the focal point of scientists all over the world. due to Folkman's discovery and learn, the chances of antiangiogenic and angiogenic treatment have broadened past melanoma to many noncancerous diseases.
This booklet represents the 1st assortment in a quantity of which Dr. Folkman is co-editor. Dr. Folkman authored approximately four hundred unique papers and greater than a hundred booklet chapters.
Dr. William Figg is the executive of the Molecular and scientific Pharmacology application on the nationwide melanoma Institute, nationwide Institutes of overall healthiness. during the last 15 years, his laboratory and hospital on the NCI have inquisitive about the advance of angiogenesis inhibitors. Dr. Figg has released greater than 380 publications.
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Additional info for Angiogenesis: An Integrative Approach From Science to Medicine
Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res 2000; 60:1878. 122. Klement G, Baruchel S, Rak J, Man S, Clark K, Hicklin DJ, Bohlen P, Kerbel RS. Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity. J Clin Invest 2000; 105:R15. 123. Hanahan D, Bergers G, Bergsland E. Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice.
Almog N, Henke V, Flores L, Hlatky L, Kung AL, Wright RD, Berger R, Hutchinson L, Naumov GN, Bender E, Akslen LA, Achilles EG, Folkman J. Prolonged dormancy of human liposarcoma is associated with impaired tumor angiogenesis. FASEB J 2006; 20: 947. 129. Naumov GN, Bender E, Zurakowski D, Kang SY, Sampson D, Flynn E, Watnick RS, Straume O, Akslen LA, Folkman J, Almog N. A model of human tumor dormancy: an angiogenic switch from the nonangiogenic phenotype. J Natl Cancer Inst 2006; 98: 316–325. 130.
Proc Nat Acad Sci USA 1994; 91(9):3964. Folkman J, Mulliken JB, Ezekowitz RAB. Antiangiogenic therapy of haemangiomas with interferon A. In: Stuart-Harris R, Penny R, eds. The Clinical Applications of the Interferons. Chapman & Hall Medical, London 1997; 255. Folkman J. Endogenous angiogenesis inhibitors. Acta Pathologica, Microbiologica, et Immunologica Scandinavica 2004; 112:496. Nyberg P, Xie L, Kalluri R. Endogenous inhibitors of angiogenesis. Cancer Res 2005; 65:3967. Abdollahi A, Hahnfeldt P, Maercker C, Gröne, HJ, Debus J, Ansorge W, Folkman J, Hlatky L, Huber PE.
Angiogenesis: An Integrative Approach From Science to Medicine by Judah Folkman (auth.), William D. Figg, Judah Folkman (eds.)